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Can you take paracetamol ibuprofen and codeine at the same time? It's safe to take combined ibuprofen and codeine with paracetamol. Do not take combined ibuprofen and codeine with ibuprofen, aspirin or naproxen. Ibuprofen, aspirin and naproxen belong to the same group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). What happens when you take too much paracetamol? Signs of paracetamol overdose include drowsiness, coma, seizures, abdominal pain, nausea and vomiting. There is only a small difference between the maximum daily dose of paracetamol and an overdose, which can cause liver damage.
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